Clinical application of remote ischemic preconditioning.

@article{Kloner2009ClinicalAO,
  title={Clinical application of remote ischemic preconditioning.},
  author={Robert A. Kloner},
  journal={Circulation},
  year={2009},
  volume={119 6},
  pages={776-8}
}
Ischemic preconditioning1 has been shown to reliably reduce ischemic myocardial cell necrosis in a host of animal models.2 Although preconditioning is one of the most powerful and reproducible phenomena in cardioprotection, it has not readily translated to routine clinical use. One issue is that the timing of the long duration of ischemia must be known in advance and the treatment must be applied before the long duration of ischemia. Thus, although evidence suggests that preinfarction ischemia… CONTINUE READING

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