Clinical application of polymerase chain reaction to diagnose Clostridium difficile in hospitalized patients with diarrhea.

Abstract

BACKGROUND & AIMS Clostridium difficile is a common cause of diarrhea in hospitalized patients and is associated with significant morbidity and cost. The current diagnostic standard, enzyme immunoassay (EIA), has low sensitivity, leading to duplicate testing and empiric treatment. We sought to show the usefulness and potential cost effectiveness of… (More)

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