Clinical application of next-generation sequencing in preimplantation genetic diagnosis cycles for Robertsonian and reciprocal translocations

Abstract

The purpose of this study was to apply next-generation sequencing (NGS) technology to identify chromosomally normal embryos for transfer in preimplantation genetic diagnosis (PGD) cycles for translocations. A total of 21 translocation couples with a history of infertility and repeated miscarriage presented at our PGD clinic for 24-chromosome embryo testing… (More)
DOI: 10.1007/s10815-016-0724-2

Topics

5 Figures and Tables

Cite this paper

@article{Zhang2016ClinicalAO, title={Clinical application of next-generation sequencing in preimplantation genetic diagnosis cycles for Robertsonian and reciprocal translocations}, author={Wenke Zhang and Ying Liu and Li Wang and Hui Wang and Minyue Ma and Mengnan Xu and Xiaofei Xu and Zhiying Gao and Jinliang Duan and David S Cram and Yuan-Qing Yao}, journal={Journal of Assisted Reproduction and Genetics}, year={2016}, volume={33}, pages={899-906} }