Clinical and ultrastructural studies of Romberg's hemifacial atrophy.

  title={Clinical and ultrastructural studies of Romberg's hemifacial atrophy.},
  author={Jay M Pensler and George Murphy and John Butler Mulliken},
  journal={Plastic and reconstructive surgery},
  volume={85 5},
  pages={669-74; discussion 675-6}
Romberg's disease is an uncommon and poorly understood condition manifested by progressive hemifacial atrophy of skin, soft tissue, and bone. In order to better define the natural history and anatomic variation of this disorder, we evaluated 41 patients by history, physical examination, and facial radiographs. Light microscopic studies were performed on tissue from 19 patients, and ultrastructural analysis was performed on specimens from 6 patients. The average age at inception of the disease… CONTINUE READING


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