Clinical and toxicological consequences of the inductive potential of ethanol

@article{Klotz1998ClinicalAT,
  title={Clinical and toxicological consequences of the inductive potential of ethanol},
  author={U. Klotz and E. Ammon},
  journal={European Journal of Clinical Pharmacology},
  year={1998},
  volume={54},
  pages={7-12}
}
  • U. Klotz, E. Ammon
  • Published 1998
  • Medicine, Chemistry
  • European Journal of Clinical Pharmacology
  • Abstract Variability in drug metabolism is an important factor that accounts for individual responsiveness to xenobiotics. Enzyme induction which leads to a more rapid elimination of foreign compounds and to a more extensive formation of potentially active metabolites significantly contributes to large interindividual variability in drug effects.Ethanol is consumed worldwide in tremendous amounts and is an effective inducer of hepatic drug metabolism, especially involving pathways accomplished… CONTINUE READING
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