Clinical and research diagnostic criteria for Alzheimer's disease.

  title={Clinical and research diagnostic criteria for Alzheimer's disease.},
  author={Marie Sarazin and Leonardo Cruz de Souza and St{\'e}phane Leh{\'e}ricy and Bruno Dubois},
  journal={Neuroimaging clinics of North America},
  volume={22 1},
In contrast with the previous criteria published in 1984 by the National Institute of Neurological and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association, the new criteria proposed in 2007 incorporated in the diagnostic framework the use of biomarkers that are able to assess the underlying pathophysiologic mechanism. The combination of clinical and biologic approaches makes a diagnosis of Alzheimer's disease possible before the dementia stage. The… CONTINUE READING


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