Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis
@article{Lucchinetti2008ClinicalAR, title={Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis}, author={Claudia F. Lucchinetti and Ralitza H. Gavrilova and Imke Metz and Joseph E. Parisi and Bernd W. Scheithauer and S. Weigand and Kristine M. Thomsen and Jayawant Mandrekar and Ayşe G{\"u}l Koçak Altıntaş and Bradley James Erickson and Fatima Barbara K{\"o}nig and Caterina Giannini and Hans Lassmann and Linda Linbo and S. J. Pittock and Wolfgang Br{\"u}ck}, journal={Brain}, year={2008}, volume={131}, pages={1759 - 1775} }
Atypical imaging features of multiple sclerosis lesions include size >2 cm, mass effect, oedema and/or ring enhancement. This constellation is often referred to as ‘tumefactive multiple sclerosis’. Previous series emphasize their unifocal and clinically isolated nature, however, evolution of these lesions is not well defined. Biopsy may be required for diagnosis. We describe clinical and radiographic features in 168 patients with biopsy confirmed CNS inflammatory demyelinating disease (IDD…
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