Clinical and psychological characteristics of the initial cohort of the Dominantly Inherited Alzheimer Network (DIAN).

@article{Storandt2014ClinicalAP,
  title={Clinical and psychological characteristics of the initial cohort of the Dominantly Inherited Alzheimer Network (DIAN).},
  author={Martha Storandt and David A. Balota and Andrew J Aschenbrenner and John C. Morris},
  journal={Neuropsychology},
  year={2014},
  volume={28 1},
  pages={
          19-29
        }
}
OBJECTIVE The purpose was to describe clinical, cognitive, and personality characteristics at baseline assessment of 249 participants, 19 to 60 years of age, in a multinational longitudinal study of autosomal dominant Alzheimer's disease (ADAD). METHOD Participants (74% cognitively normal) were from ADAD families with mutations in 1 of 3 genes (APP, PSEN1, or PSEN2). Mixed model analyses, including family as a random variable and controlling for years from expected time of symptomatic onset… CONTINUE READING
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