Clinical and pathological features of alcohol-related brain damage

  title={Clinical and pathological features of alcohol-related brain damage},
  author={N. Zahr and Kimberley Louise Kaufman Alexander-Kaufman and C. Harper},
  journal={Nature Reviews Neurology},
  • N. Zahr, Kimberley Louise Kaufman Alexander-Kaufman, C. Harper
  • Published 2011
  • Medicine
  • Nature Reviews Neurology
  • One of the sequelae of chronic alcohol abuse is malnutrition. Importantly, a deficiency in thiamine (vitamin B1) can result in the acute, potentially reversible neurological disorder Wernicke encephalopathy (WE). When WE is recognized, thiamine treatment can elicit a rapid clinical recovery. If WE is left untreated, however, patients can develop Korsakoff syndrome (KS), a severe neurological disorder characterized by anterograde amnesia. Alcohol-related brain damage (ARBD) describes the effects… CONTINUE READING
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