Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease.

@article{Pettegrew1995ClinicalAN,
  title={Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer's disease.},
  author={Jay W. Pettegrew and William E. Klunk and Kanagasabai Panchalingam and Julian N. Kanfer and Richard J. McClure},
  journal={Neurobiology of aging},
  year={1995},
  volume={16 1},
  pages={1-4}
}
In a double-blind, placebo study, acetyl-L-carnitine was administered to 7 probable Alzheimer's disease patients who were then compared by clinical and 31P magnetic resonance spectroscopic measures to 5 placebo-treated probable AD patients and 21 age-matched healthy controls over the course of 1 year. Compared to AD patients on placebo, acetyl-L-carnitine-treated patients showed significantly less deterioration in their Mini-Mental Status and Alzheimer's Disease Assessment Scale test scores… CONTINUE READING
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