Clinical and microbiological effects of azithromycin in the treatment of generalized chronic periodontitis: a randomized placebo-controlled clinical trial.

@article{Sampaio2011ClinicalAM,
  title={Clinical and microbiological effects of azithromycin in the treatment of generalized chronic periodontitis: a randomized placebo-controlled clinical trial.},
  author={Eduardo B Sampaio and Marcelo Rocha and Luciene Cristina de Figueiredo and M Faveri and Poliana Mendes Duarte and Eisla Alline Gomes Lira and Magda Feres},
  journal={Journal of clinical periodontology},
  year={2011},
  volume={38 9},
  pages={838-46}
}
AIM To evaluate the effects of systemic azithromycin (AZM) as an adjunct to scaling and root planing (SRP) in the treatment of generalized chronic periodontitis (ChP). METHODS Forty subjects were randomly assigned to receive SRP alone or combined with AZM (500 mg/day) for 5 days (n=20/group). Clinical and microbiological examinations were performed at baseline, 6 months and 1-year post-SRP. Nine plaque samples per subject were analysed by checkerboard DNA-DNA hybridization for 40 bacterial… CONTINUE READING

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