Clinical and microbiologic effects of subgingival controlled-release delivery of chlorhexidine chip in the treatment of periodontitis: a multicenter study.

@article{Paolantonio2008ClinicalAM,
  title={Clinical and microbiologic effects of subgingival controlled-release delivery of chlorhexidine chip in the treatment of periodontitis: a multicenter study.},
  author={Michele Paolantonio and Matteo D'Angelo and Roberto Felice Grassi and Giuseppe Perinetti and Raffaele Piccolomini and Giuseppe Pizzo and Marco Annunziata and Domenico D'Archivio and Simonetta D'ercole and Gianna Maria Nardi and Luigi Guida},
  journal={Journal of periodontology},
  year={2008},
  volume={79 2},
  pages={271-82}
}
BACKGROUND The main therapeutic approach for periodontal diseases is mechanical treatment of root surfaces via scaling and root planing (SRP). Multicenter clinical trials have demonstrated that the adjunctive use of a chlorhexidine (CHX) chip is effective in improving clinical results compared to SRP alone. However, some recent studies failed to confirm these clinical results, and conflicting results were reported regarding the effects of the CHX chip on subgingival microflora. The aim of this… CONTINUE READING

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