Clinical and immunogenetic characteristics of European multicase rheumatoid arthritis families.

@article{Balsa2001ClinicalAI,
  title={Clinical and immunogenetic characteristics of European multicase rheumatoid arthritis families.},
  author={Alejandro Balsa and P. Barrera and Ren{\'e} Westhovens and Helena Alves and K Maenaut and Dora Pascual-Salcedo and Francois H Cornelis and Thomas Bardin and Lucrezia Riente and Timothy R D J Radstake and Gisele Madeira Duboc de Almeida and V Lepage and C Stravopoulos and Marijke Spaepen and Antonio Lopes-Vaz and Derek Charron and Mario Alberto Sesma Mart{\'i}nez and Jacques Prudhomme and Paola Migliorini and Peter J Fritz},
  journal={Annals of the rheumatic diseases},
  year={2001},
  volume={60 6},
  pages={573-6}
}
OBJECTIVE To describe the characteristics of a new set of European families with affected sib pairs (ASP) collected by the European Consortium on Rheumatoid Arthritis Families (ECRAF) to replicate the results of our first genome scan. Potential gradients for disease severity in Europe and concordance within families were studied. PATIENTS AND METHODS From 1996 to 1998 European white families with at least two affected siblings were enrolled in the study. Demographic (sex, age at onset… CONTINUE READING

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