Clinical and genetic issues in familial dilated cardiomyopathy.

  title={Clinical and genetic issues in familial dilated cardiomyopathy.},
  author={Emily L Burkett and Ray E. Hershberger},
  journal={Journal of the American College of Cardiology},
  volume={45 7},
Idiopathic dilated cardiomyopathy (IDC) is characterized by left ventricular dilatation and systolic dysfunction after known causes have been excluded. Idiopathic dilated cardiomyopathy occurring in families, or familial dilated cardiomyopathy (FDC), may occur in 20% to 50% of IDC cases. Sixteen genes have been shown to cause autosomal dominant FDC, but collectively may account for only a fraction of genetic causation; it is anticipated that additional genes causative of FDC will be discovered… CONTINUE READING
160 Citations
113 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 160 extracted citations


Publications referenced by this paper.
Showing 1-10 of 113 references

Similar Papers

Loading similar papers…