Clinical and genetic factors associated with sacroiliitis in Crohn's disease

@article{Peeters2008ClinicalAG,
  title={Clinical and genetic factors associated with sacroiliitis in Crohn's disease},
  author={Harald Peeters and Bert Vander Cruyssen and Herman Mielants and Kurt de Vlam and S{\'e}verine Vermeire and Edouard Louis and Paul J. Rutgeerts and Jacques Belaiche and Martine De Vos},
  journal={Journal of Gastroenterology and Hepatology},
  year={2008},
  volume={23}
}
Background and Aim:  Radiographic sacroiliitis (SI), often asymptomatic, is considered the most frequent extra‐intestinal manifestation (EIM) of Crohn's disease (CD). Data on the association of SI with other clinical features of CD are limited. Association of SI with CARD15 polymorphisms has recently been suggested. In a multicenter study, we investigated the association of SI in CD patients with clinical phenotypes, other EIM and CARD15 polymorphisms. 

Sacroiliitis is common in Crohn's disease patients with perianal or upper gastrointestinal involvement.

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...

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In 89 patients with inflammatory bowel disease, only one out of 11 patients with radiographic sacroiliitis was found to possess the HLA B27 antigen, while three out of four patients with ankylosing

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