Clinical and epidemiological implications of swine hepatitis E virus infection

@article{Wu2000ClinicalAE,
  title={Clinical and epidemiological implications of swine hepatitis E virus infection},
  author={J. Wu and C. Chen and T. Chiang and I. Sheen and J. Chen and W. Tsai and Y. Huang and S. Lee},
  journal={Journal of Medical Virology},
  year={2000},
  volume={60}
}
  • J. Wu, C. Chen, +5 authors S. Lee
  • Published 2000
  • Biology, Medicine
  • Journal of Medical Virology
In nonendemic areas, most patients with acute hepatitis E were infected through traveling to endemic areas. However, some patients did not have a history of foreign travel before infection. Furthermore, high seroprevalence rates of antibody to hepatitis E virus (anti‐HEV) were found in the general adult population in some countries without any recorded outbreak of hepatitis E. The significance of anti‐HEV assay in these subjects remains obscure. To study if swine might be a source of HEV… Expand
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References

SHOWING 1-10 OF 29 REFERENCES
Genetic and Experimental Evidence for Cross-Species Infection by Swine Hepatitis E Virus
TLDR
The results suggested that swine HEV may infect humans, and in a reciprocal experiment, specific-pathogen-free pigs were experimentally infected with the US-2 strain of human HEV that is genetically similar to swineHEV. Expand
A novel virus in swine is closely related to the human hepatitis E virus.
  • X. Meng, R. Purcell, +6 authors S. Emerson
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1997
TLDR
The discovery of swine HEV not only has implications for HEV vaccine development, diagnosis, and biology, but also raises a potential public health concern for zoonosis or xenozoonosis following xenotransplantation with pig organs. Expand
The impact of traveling to endemic areas on the spread of hepatitis E virus infection: Epidemiological and molecular analyses
TLDR
E Epidemiological and molecular analyses strongly indicate that most cases of HEV infection originated from travel to HEV‐endemic areas, andHEV infection does occur in this area. Expand
Molecular cloning and sequencing of the Mexico isolate of hepatitis E virus (HEV).
TLDR
Knowing the extent of the sequence variation encountered with HEV will not only aid in the future development of diagnostic and vaccine reagents but also further the understanding of how HEV strain variation might impact the pathological outcome of infection. Expand
Detection of hepatitis E virus infections among domestic swine in the Kathmandu Valley of Nepal.
TLDR
Results indicate that HEV is a zoonotic virus, and that swine are among its natural hosts. Expand
Outbreak of acute hepatitis E virus infection among military personnel in northern Ethiopia
TLDR
The need for an easily available, inexpensive serologic test for HEV infection, protection of water supplies from fecal contamination, adequate chlorination and/or boiling of drinking water, and health education about personal and environmental hygiene, especially in communities at high risk, is emphasized. Expand
Hepatitis E virus: identification of type-common epitopes
TLDR
The isolation, by serologic screening, of two cDNA clones derived from a fecal sample collected during a 1986 outbreak of ET-NANBH in Telixtac, Mexico represent the initial cloning of the Mexico strain of HEV. Expand
Characterization of a prototype strain of hepatitis E virus.
TLDR
A strain of hepatitis E virus (SAR-55) implicated in an epidemic of enterically transmitted non-A, non-B hepatitis, now called hepatitis E, was characterized extensively and identified as hypervariable. Expand
Seroreactivity to hepatitis E virus in areas where the disease is not endemic
If the occurrence of hepatitis E virus antibody (anti-HEV) in regions where the disease is not endemic represents infection, rates may be greater in high-risk populations and behavioral correlatesExpand
Experimental infection of the laboratory rat with the hepatitis E virus
TLDR
It is confirmed that HEV can replicate in laboratory rats and suggest new tissue sites for HEV replication and histopathology attributable to the inoculum in liver, spleen, and lymph nodes. Expand
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