Corpus ID: 21138527

Clinical and diagnostic management of toxoplasmosis in the immunocompromised patient.

@article{Contini2008ClinicalAD,
  title={Clinical and diagnostic management of toxoplasmosis in the immunocompromised patient.},
  author={C. Contini},
  journal={Parassitologia},
  year={2008},
  volume={50 1-2},
  pages={
          45-50
        }
}
With the advent of the highly active antiretroviral therapy (HAART), the natural course of HIV infection has markedly changed and opportunistic infections including toxoplasmosis have declined and modified in presentation, outcome and incidence. However, TE is a major cause of morbidity and mortality especially in resource-poor settings but also a common neurological complication in some countries despite the availability of HAART and effective prophylaxis. In most cases toxoplasmosis occurs in… Expand
Evaluation of seroepidemiological toxoplasmosis in HIV/AIDS patients in the south of Brazil.
TLDR
The study population is at high risk of clinical toxoplasmosis, because of both reactivation of infection in the seropositive patients who do not make a regular use of HAART, and primo-infection in seronegative patients worsened by an unawareness of the modes of infection reported in this study. Expand
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Current clinical understanding of OT including typical and atypical manifestations, patient characteristics which influence the course of disease and treatment options are discussed, and a brief outlook is given in which direction OT research should be headed in the future. Expand
Molecular and Serological Evaluation of Toxoplasmosis in AIDS Cases in Southwest Iran
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A high prevalence of acute and chronic toxoplasmosis in HIV-positive patients was showed and the findings suggested using IgG-avidity test in a condition where PCR testing is impossible, particularly to distinguish recently acquired infection from past infection. Expand
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The rate of toxoplasmosis infection in HIV positive patients is high and immediate treatment of these patients is essential in rising specific antibody cases that may cause toxoplasmaic encephalitis resulting from its reactivation. Expand
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Information on the diagnosis and treatment of nonenteric protozoal diseases in immunocompromised people, with a focus on patients infected with HIV is reviewed. Expand
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Although current evidence does not allow a definitive recommendation, administration of TMP-SMX for primary prophylaxis and treatment of TE in patients with HIV infection is consistent with the available data. Expand
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Although this study shows a TE incidence and mortality reduction in the AIDS cohort after HAART, the incidence was higher than those reported in the United States AIDS patients, which might explain the lack of impact of this intervention. Expand
Successful Treatment of Pulmonary and Cerebral Toxoplasmosis Associated with Pneumocystis Pneumonia in an HIV Patient
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An uncommon case of an AIDS patient with both pulmonary and cerebral toxoplasmosis associated with pneumocystis pneumonia is reported, which was successful treated by trimethoprim/sulfamethoxaxole in conjunction with an early reintroduction of cART, and without IRIS development. Expand
Sero-molecular evaluation of Toxoplasma gondii infection among HIV-positive patients.
BACKGROUND Toxoplasmosis is one of the most common comorbidities in HIV-positive patients with CD4+ T lymphocytes below 200 cells/μl. Early diagnosis and treatment of toxoplasmosis reduces theExpand
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TLDR
This article focuses on Toxoplasma gondii genetic diversity and its possible relationship with disease presentation; host responses to the parasite antigens; host immunosupression in HIV and cerebral toxoplasmosis as well as different diagnostic methods; clinical and radiological features; treatment; and the direction that studies on cerebral toxplasmosis will likely take in the future. Expand
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