Clinical and biologic behavior of bone metastases from differentiated thyroid carcinoma.

@article{Marcocci1989ClinicalAB,
  title={Clinical and biologic behavior of bone metastases from differentiated thyroid carcinoma.},
  author={Claudio Marcocci and F. Rossi Pacini and Rossella Elisei and Ernestina Schipani and Claudia Ceccarelli and Paolo Miccoli and M Arganini and Aldo Pinchera},
  journal={Surgery},
  year={1989},
  volume={106 6},
  pages={960-6}
}
Thirty (3.8%) of 780 patients with differentiated thyroid cancer seen between 1970 and 1987 had bone metastases. The primary tumor was follicular in 26 patients and papillary in four. Mean age at diagnosis was 61 years. The manifestation of bone metastases was the presenting symptom in 18 patients (60%). Treatment included total thyroidectomy, levothyroxine sodium therapy, and radioactive iodine treatments. Twenty-seven patients had bone metastases from the initial observation, with 44 sites… CONTINUE READING
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