Clinical and biochemical investigations and molecular analysis of subjects with mutations in the androgen receptor gene

@article{Weidemann1996ClinicalAB,
  title={Clinical and biochemical investigations and molecular analysis of subjects with mutations in the androgen receptor gene},
  author={W. Weidemann and B. Linck and H. Haupt and B. Mentrup and G. Romalo and K. Stockklauser and A. Brinkmann and H. Schweikert and K. Spindler},
  journal={Clinical Endocrinology},
  year={1996},
  volume={45}
}
  • W. Weidemann, B. Linck, +6 authors K. Spindler
  • Published 1996
  • Biology, Medicine
  • Clinical Endocrinology
  • OBJECTIVE Androgen insensitivity syndromes (AIS) in subjects with 46,XY karyotype and normal or even elevated androgen blood levels are characterized by various aberrations in male differentiation and virilization. AIS is often accompanied by a broad spectrum of abnormal binding characteristics of the androgen receptor (AR). In order to investigate the correlation between the degree of virilization defect and the type of androgen binding abnormalities and/or the nature of the mutation in the AR… CONTINUE READING
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