Clinical and anatomical spectrum in XX sex reversed patients. Relationship to the presence of Y specific DNA-sequences.

@article{Boucekkine1994ClinicalAA,
  title={Clinical and anatomical spectrum in XX sex reversed patients. Relationship to the presence of Y specific DNA-sequences.},
  author={Chafika Boucekkine and Jean Edmond Toublanc and Nacer Abbas and S Chaabouni and S Ouahid and M Semrouni and Francis Jaubert and Marianne Toublanc and Ken Mcelreavey and Eric Vilain},
  journal={Clinical endocrinology},
  year={1994},
  volume={40 6},
  pages={733-42}
}
OBJECTIVE Testicular differentiation can occur in the absence of the Y chromosome giving XX sex-reversed males. Although Y chromosomal sequences can be detected in the majority of male subjects with a 46,XX karyotype, several studies have shown that approximately 10% of patients lack Y material including the SRY gene. The aim of this study was to see if the classification of XX sex-reversed individuals into three groups, Y-DNA-positive phenotypically normal XX males, Y-DNA-negative XX males… CONTINUE READING
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