Corpus ID: 42414763

Clinical and Social Aspects of Leprosy ( Hansen ’ s Disease ) and Contemporary Challenges to Elimination

@inproceedings{White2017ClinicalAS,
  title={Clinical and Social Aspects of Leprosy ( Hansen ’ s Disease ) and Contemporary Challenges to Elimination},
  author={Cassandra L. White},
  year={2017}
}
Although there is an effective treatment for Hansen’s Disease (leprosy), there are still 200,000 or more cases reported each year around the world. This paper explores some of the future challenges to controlling Hansen’s Disease transmission and preventing disability. These barriers include the long incubation period of the disease; the development of disabilities post-“cure”; problems with case detection and coverage in remote areas; the existence of an animal host for the disease in the… Expand

References

SHOWING 1-10 OF 23 REFERENCES
Leprosy as a neurological disease
TLDR
The focus moves from controlling the infectious disease of the skin to the identifi cation and treatment of nerve impairment, leprosy disability—and therefore discrimination—will not be eradicated any time soon. Expand
The Continuing Challenges of Leprosy
TLDR
This review focuses on recent advances in the understanding of M. leprae and the host response to it, especially concerning molecular identification of M.'s genome, transcriptome, and proteome, its mechanisms of microbial resistance, and recognition of strains by variable-number tandem repeat analysis. Expand
What do we actually know about leprosy worldwide?
TLDR
Although the zero-transmission strategy is highly desirable, comprehension and acknowledgment of the real worldwide leprosy situation is imperative and imperative for the elimination target to become meaningless. Expand
Infection with Mycobacterium lepromatosis
  • D. Scollard
  • Medicine, Biology
  • The American journal of tropical medicine and hygiene
  • 2016
TLDR
Based on the limited experience of the National Hansen's Disease Programs with the treatment and follow-up of a small number of patients with this infection in the United States and Canada, it appears that infection with M. lepromatosis manifests clinically and histologically with a wide spectrum of lesions that is well described in leprosy. Expand
Spatial epidemiology and serologic cohorts increase the early detection of leprosy
TLDR
Targeted screening involving school-based surveillance planned using results obtained by spatial analysis and targeted household and individual continuous surveillance based on serologic data should be applied to increase the early detection of new leprosy cases. Expand
Silent neuropathy in leprosy: an epidemiological description.
TLDR
Some epidemiological evidence is presented that suggests that SN cannot be equated with a 'reversal reaction expressing itself in the nerves', and it is recommended that all patients should have a nerve function assessment at every visit to the clinic at least during their first year of treatment. Expand
Five-year experience with type 1 and type 2 reactions in Hansen disease at a US travel clinic.
TLDR
This group of patients needs long-term clinical monitoring even after completion of MDT because of the need to continue either anti-inflammatory therapy, presence of severe neurologic sequelae after reactions, or the potential occurrence of late leprosy reactions. Expand
The Burden of New Leprosy Cases in India: A Population-Based Survey in Two States
TLDR
The survey suggested that burden of new case detection rate of leprosy in India per 10,000 population could be 4.41 in comparison to 1.09 as per government records, and this suggests that the information, education, and communication based approaches have a very minimal effect. Expand
Investment case concepts in leprosy elimination: A systematic review.
TLDR
The current WHO road map for leprosy elimination is too vague and needs further structuring through a thoroughly prepared LEIC, which is based on Eradication Investment Case guidelines. Expand
Leprosy among Patient Contacts: A Multilevel Study of Risk Factors
TLDR
Biological and social factors appear to be associated with leprosy among co-prevalent cases, whereas the factors related to the infectious load and proximity with the index case were associated withLeprosy that appeared in the incident cases during follow-up. Expand
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