Clinical and Population Studies Long-Term Effects of Chlorthalidone Versus Hydrochlorothiazide on Electrocardiographic Left Ventricular Hypertrophy in the Multiple Risk Factor Intervention Trial

Abstract

Chlorthalidone (CTD) reduces 24-hour blood pressure more effectively than hydrochlorothiazide (HCTZ), but whether this influences electrocardiographic left ventricular hypertrophy is uncertain. One source of comparative data is the Multiple Risk Factor Intervention Trial, which randomly assigned 8012 hypertensive men to special intervention (SI) or usual… (More)

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@inproceedings{Ernst2011ClinicalAP, title={Clinical and Population Studies Long-Term Effects of Chlorthalidone Versus Hydrochlorothiazide on Electrocardiographic Left Ventricular Hypertrophy in the Multiple Risk Factor Intervention Trial}, author={Michael E. Ernst and James D. Neaton and Richard H. Grimm and Gary B. Collins and William Thomas and Elsayed Z Soliman and Ronald J. Prineas}, year={2011} }