Clinical and Economic Outcomes of Patients with Type 2 Diabetes on Multiple Daily Injections of Basal-bolus Insulin (MDI) Therapy: A Retrospective Cohort Study.

@article{Brixner2019ClinicalAE,
  title={Clinical and Economic Outcomes of Patients with Type 2 Diabetes on Multiple Daily Injections of Basal-bolus Insulin (MDI) Therapy: A Retrospective Cohort Study.},
  author={D. Brixner and A. Ermakova and Y. Xiong and R. Sieradzan and N. Sacks and P. Cyr and S. Taylor},
  journal={Clinical therapeutics},
  year={2019},
  volume={41 2},
  pages={
          303-313.e1
        }
}
PURPOSE Therapy for patients with type 2 diabetes (T2DM) not achieving hemoglobin (Hb) A1c targets may progress from an oral antidiabetic drug (OAD) to added basal insulin and then to multiple daily injections of basal-bolus insulin (MDI); however, the relative clinical and economic burden experienced by patients prescribed MDI for T2DM is not well quantified. The intent of this work was to describe direct medical costs, health care resource utilization, and glycemic control in patients with… Expand
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