Clinical amyloid imaging in Alzheimer's disease.

@article{Herholz2011ClinicalAI,
  title={Clinical amyloid imaging in Alzheimer's disease.},
  author={Karl Herholz and Klaus P. Ebmeier},
  journal={The Lancet. Neurology},
  year={2011},
  volume={10 7},
  pages={667-70}
}
BACKGROUND The hypothesis that amyloid deposition is the leading cause of Alzheimer's disease (AD) is supported by findings in transgenic animal models and forms the basis of clinical trials of anti-amyloid agents. According to this theory, amyloid deposition causes severe damage to neurons many years before onset of dementia via a cascade of several downstream effects. This hypothesis has, however, not yet been directly tested in human beings because of the very limited possibility of… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 78 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 49 references

Use of fl orbetapirPET for imaging betaamyloid pathology

  • CM Clark, JA Schneider, BJ Bedell
  • JAMA
  • 2011

1 8Ffl utemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment : a phase 2 trial

  • R Vandenberghe, K VanLaere, A Ivanoiu
  • Ann Neurol
  • 2010

Similar Papers

Loading similar papers…