Clinical Usefulness of Serum Krebs von den Lungen-6 for Detecting Chronic Aspiration in Children with Severe Motor and Intellectual Disabilities.

@article{Wakamoto2015ClinicalUO,
  title={Clinical Usefulness of Serum Krebs von den Lungen-6 for Detecting Chronic Aspiration in Children with Severe Motor and Intellectual Disabilities.},
  author={Hiroyuki Wakamoto and Nozomi Sano and Yoshiaki Yano and Shinya Sakai and Takanori Kikuchi and Mitsumasa Fukuda and Takehiko Morimoto and Eiichi Ishii},
  journal={The Journal of pediatrics},
  year={2015},
  volume={167 5},
  pages={
          1136-42
        }
}
OBJECTIVE To determine whether the serum level of Krebs von den Lungen-6 (KL-6), a circulating high-molecular weight glycoprotein and a diagnostic biomarker of interstitial lung diseases, is a clinically useful biomarker for detecting chronic aspiration in children with severe motor and intellectual disabilities (SMIDS). STUDY DESIGN Children with SMIDS undergoing videofluorography for assessment of dysphagia were prospectively evaluated. Based on the videofluorography results, the… CONTINUE READING
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