Clinical Treatment of Radiotherapy Tissue Damage by Lipoaspirate Transplant: A Healing Process Mediated by Adipose-Derived Adult Stem Cells

@article{Rigotti2007ClinicalTO,
  title={Clinical Treatment of Radiotherapy Tissue Damage by Lipoaspirate Transplant: A Healing Process Mediated by Adipose-Derived Adult Stem Cells},
  author={G. Rigotti and A. Marchi and M. Gali{\`e} and G. Baroni and D. Benati and M. Krampera and A. Pasini and A. Sbarbati},
  journal={Plastic and Reconstructive Surgery},
  year={2007},
  volume={119},
  pages={1409-1422}
}
Background: There is evidence that stem cells contribute to the restoration of tissue vascularization and organ function. The objective of this study was to assess the presence of adipose-derived adult stem cells left in their natural scaffold in the purified lipoaspirate and to assess the clinical effectiveness of lipoaspirate transplantation in the treatment of radiation side effects. Methods: This study was designed beginning with surgical procedures in 2002 and envisaging a continuous… Expand
950 Citations

Paper Mentions

Interventional Clinical Trial
This pilot study of 12 patients will test the safety and efficacy of applying autologous, adipose-derived stromal cells (ASCs), uncultured, on a Stage III or IV pressure ulcer or… Expand
ConditionsPressure Ulcer
InterventionBiological, Drug
Interventional Clinical Trial
The purpose of this study is to determine if autologous fat transplantation as a pre-treatment gives better results in breast reconstruction with implants after mastectomy and… Expand
ConditionsBreast Neoplasms
InterventionProcedure
Interventional Clinical Trial
Grafting of autologous stromal cell trial is a prospective study comparing routine fat grafting versus stromal vascular fraction enriched fat grafting.  
ConditionsMicromastia
InterventionProcedure
Interventional Clinical Trial
The primary objectives of this study is to determine whether use of a negative pressure external soft-tissue expansion system pre-operatively and post-operatively improves and… Expand
ConditionsLumpectomy, Mammaplasty, Mastectomy
InterventionDevice
Adipose-Derived Stem Cells in Radiotherapy Injury: A New Frontier
A Comprehensive In Vitro Comparison of Preparation Techniques for Fat Grafting
Stem cell enrichment does not warrant a higher graft survival in lipofilling of the breast: a prospective comparative study.
From liposuction to adipose-derived stem cells: indications and technique
Adipose-Derived Tissue in the Treatment of Dermal Fibrosis: Antifibrotic Effects of Adipose-Derived Stem Cells
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 31 REFERENCES
Long-Term survival of fat transplants: Controlled demonstrations
Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration
Fat grafting.
Comparison of Multi-Lineage Cells from Human Adipose Tissue and Bone Marrow
Circulation in the breast after radiotherapy and breast conservation.
...
1
2
3
4
...