Clinical Studies of Sparfloxacin in Odontogenic Infections

Sparfloxacin is a new quinolone derivative with excellent antimicrobial activity and a broad antibacterial spectrum against major causative organisms of odontogenic infections such as oral streptococci and anaerobic bacteria (Nakamura et al. 1989). Pharmacokinetic studies of sparfloxacin revealed a long plasma elimination half-life of approximately 16 hours… CONTINUE READING