Clinical Relevance of IgG Antibodies against Food Antigens in Crohn’s Disease: A Double-Blind Cross-Over Diet Intervention Study

  title={Clinical Relevance of IgG Antibodies against Food Antigens in Crohn’s Disease: A Double-Blind Cross-Over Diet Intervention Study},
  author={Susanne Bentz and Martin Hausmann and Heidi Piberger and Silvia Kellermeier and S. Paul and Leonhard Held and Werner Falk and Florian Obermeier and Michael W. Fried and Juergen Schölmerich and Gerhard Rogler},
  pages={252 - 264}
Background: Environmental factors are thought to play an important role in the development of Crohn’s disease (CD). Immune responses against auto-antigens or food antigens may be a reason for the perpetuation of inflammation. Methods: In a pilot study, 79 CD patients and 20 healthy controls were examined for food immunoglobulin G (IgG). Thereafter, the clinical relevance of these food IgG antibodies was assessed in a double-blind cross-over study with 40 patients. Based on the IgG antibodies, a… 

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