Clinical Pharmacokinetics of Sparfloxacin

  title={Clinical Pharmacokinetics of Sparfloxacin},
  author={J. Shimada and T. Nogita and Y. Ishibashi},
  journal={Clinical Pharmacokinetics},
  • J. Shimada, T. Nogita, Y. Ishibashi
  • Published 1993
  • Medicine
  • Clinical Pharmacokinetics
  • SummarySparfloxacin is a recently developed fluoroquinolone. The drug has shown potent antimicrobial activity against a wide range of Gram-positive and Gram-negative bacteria, glucose nonfermenters, anaerobes, Legionella spp., Mycoplasma spp., Chlamydia spp. and Mycobacterium spp. Methicillin-resistant Staphylococcus aureus is also susceptible to sparfloxacin.Plasma sparfloxacin concentrations reach a peak (Cmax) of approximately 0.7 mg/L at 3 to 5 hours after a 200mg oral dose. This is… CONTINUE READING
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