Clinical Pharmacokinetics of Quetiapine

@article{DeVane2001ClinicalPO,
  title={Clinical Pharmacokinetics of Quetiapine},
  author={C. L. DeVane and C. Nemeroff},
  journal={Clinical Pharmacokinetics},
  year={2001},
  volume={40},
  pages={509-522}
}
  • C. L. DeVane, C. Nemeroff
  • Published 2001
  • Medicine
  • Clinical Pharmacokinetics
  • Quetiapine is a dibenzothiazepine derivative that has been evaluated for management of patients with the manifestations of psychotic disorders. In pharmacokinetic studies in humans, quetiapine was rapidly absorbed after oral administration, with median time to reach maximum observed plasma concentration ranging from 1 to 2 hours. The absolute bioavailability is unknown, but the relative bioavailability from orally administered tablets compared with a solution was nearly complete.Food has… CONTINUE READING

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