Clinical Pharmacokinetics of Ibuprofen
@article{Davies1998ClinicalPO,
title={Clinical Pharmacokinetics of Ibuprofen},
author={N. M. Davies},
journal={Clinical Pharmacokinetics},
year={1998},
volume={34},
pages={101-154}
}Ibuprofen is a chiral nonsteroidal anti-inflammatory drug (NSAID) of the 2 arylpropionic acid (2-APA) class. A common structural feature of 2-APA NSAIDs is a sp3-hybridised tetrahedral chiral carbon atom within the propionic acid side chain moiety with the S-(+)-enantiomer possessing most of the beneficial anti-inflammatory activity. Ibuprofen demonstrates marked stereoselectivity in its pharmacokinetics. Substantial unidirectional inversion of the R-(−) to the S-(+) enantiomer occurs and thus… CONTINUE READING
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Interventional Clinical Trial
The investigators will examine the effectiveness of non-opioid analgesia (Paracetamol versus
Ibuprofen) in the early postpartum period
| Conditions | Pain |
|---|---|
| Intervention | Drug |
Interventional Clinical Trial
This is a single centre, randomised, double-blind, double-dummy, parallel group,
multiple-dose, active and placebo-controlled efficacy study to evaluate the efficacy and
safety of… Expand
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| Intervention | Drug, Other |
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