Clinical Pharmacokinetics of H1-Receptor Antagonists (The Antihistamines)

@article{Paton1985ClinicalPO,
  title={Clinical Pharmacokinetics of H1-Receptor Antagonists (The Antihistamines)},
  author={D. Paton and D. Webster},
  journal={Clinical Pharmacokinetics},
  year={1985},
  volume={10},
  pages={477-497}
}
SummaryThis article reviews clinical pharmacokinetic data on the H1-receptor antagonists, commonly referred to as the antihistamines. Despite their widespread use over an extendnd period, relatively little pharmacokinetic data are available for many of these drugs.A number of H1-receptor antagonists have been assayed mainly using radioimmunoassay methods. These have also generally measured metabolites to greater or lesser extents. Thus, the interpretation of such data is complex. After oral… Expand
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References

SHOWING 1-10 OF 72 REFERENCES
Clinical Pharmacokinetics of Chlorpheniramine
  • M. M. Rumore
  • Medicine
  • Drug intelligence & clinical pharmacy
  • 1984
  • 36
Metabolism of chlorpheniramine maleate in man.
  • 64
Pharmacokinetics and efficacy of chlorpheniramine in children.
  • 54
The pharmacokinetics and antihistaminic effects of brompheniramine.
  • 30
...
1
2
3
4
5
...