Clinical Pharmacokinetics of H1-Receptor Antagonists (The Antihistamines)

@article{Paton1985ClinicalPO,
  title={Clinical Pharmacokinetics of H1-Receptor Antagonists (The Antihistamines)},
  author={David M. Paton and Dianne R. Webster},
  journal={Clinical Pharmacokinetics},
  year={1985},
  volume={10},
  pages={477-497}
}
SummaryThis article reviews clinical pharmacokinetic data on the H1-receptor antagonists, commonly referred to as the antihistamines. Despite their widespread use over an extendnd period, relatively little pharmacokinetic data are available for many of these drugs.A number of H1-receptor antagonists have been assayed mainly using radioimmunoassay methods. These have also generally measured metabolites to greater or lesser extents. Thus, the interpretation of such data is complex. After oral… 

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