Clinical Pharmacokinetics of Cannabinoids

@inproceedings{Grotenhermen2003ClinicalPO,
  title={Clinical Pharmacokinetics of Cannabinoids},
  author={Franjo Grotenhermen},
  year={2003}
}
Absorption and metabolism of tetrahydrocannabinol (THC) vary as a function of route of administration. Pulmonary assimilation of inhaled THC causes a maximum plasma concentration within minutes, while psychotropic effects start within seconds to a few minutes, reach a maximum after 15 to 30 minutes, and taper off within 2 to 3 hours. Following oral ingestion, psychotropic effects set in with a delay of 30 to 90 minutes, reach their maximum after 2 to 3 hours, and last for about 4 to 12 hours… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 109 references

Optimization of in vitro experimental conditions for measuring the percutaneous absorption of ∆9-THC, cannabidiol, and WIN55,212-2

A. Stinchcomb, P. Challapalli, K. Harris, J. Browe.
2001 Symposium on the Cannabinoids. Burlington Vermont: International Cannabinoid Research Society, 2001, abstr. 161. • 2001
View 5 Excerpts
Highly Influenced

oral and intravenous administration and smoking

A. Ohlsson, M. Widman, S. Carlsson, T. Ryman, C. Strid
Clin Pharmacol Ther • 1980
View 17 Excerpts
Highly Influenced

Clinical pharmacokinetics of escalating i.v. doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers.

International journal of clinical pharmacology and therapeutics • 1997
View 5 Excerpts
Highly Influenced

Galetto, and the DATRI 004 Study Group

J. G. Timpone, D. J. Wright, +3 authors G. J. Mayers
AIDS Res Hum Retroviruses • 1997
View 5 Excerpts
Highly Influenced

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