Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation

@article{Staatz2004ClinicalPA,
  title={Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation},
  author={C. Staatz and S. Tett},
  journal={Clinical Pharmacokinetics},
  year={2004},
  volume={43},
  pages={623-653}
}
  • C. Staatz, S. Tett
  • Published 2004
  • Medicine
  • Clinical Pharmacokinetics
  • The aim of this review is to analyse critically the recent literature on the clinical pharmacokinetics and pharmacodynamics of tacrolimus in solid organ transplant recipients.Dosage and target concentration recommendations for tacrolimus vary from centre to centre, and large pharmacokinetic variability makes it difficult to predict what concentration will be achieved with a particular dose or dosage change. Therapeutic ranges have not been based on statistical approaches. The majority of… CONTINUE READING
    602 Citations
    Pharmacokinetics and pharmacodynamics of tacrolimus in liver transplant recipients: inside the white blood cells.
    • 21
    • PDF
    [Individualized dosage regimen of immunosuppressive drugs based on pharmacokinetic and pharmacodynamic analysis].
    • M. Fukudo
    • Chemistry, Medicine
    • Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan
    • 2007
    • 4
    • PDF
    Clinical Pharmacokinetics of Once-Daily Tacrolimus in Solid-Organ Transplant Patients
    • 51
    Population pharmacokinetic analysis of tacrolimus in the first year after pediatric liver transplantation
    • 24
    • Highly Influenced
    • PDF

    References

    SHOWING 1-10 OF 311 REFERENCES
    Population pharmacokinetics of tacrolimus in Asian paediatric liver transplant patients.
    • 51
    Toward better outcomes with tacrolimus therapy: Population pharmacokinetics and individualized dosage prediction in adult liver transplantation
    • C. Staatz, C. Willis, P. Taylor, S. Lynch, S. Tett
    • Medicine
    • Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society
    • 2003
    • 61
    Tacrolimus pharmacokinetics in BMT patients
    • 41
    • PDF
    Population pharmacokinetics of tacrolimus in adult recipients receiving living-donor liver transplantation
    • 86
    Clinical Utility of Monitoring Tacrolimus Blood Concentrations in Liver Transplant Patients
    • 126
    • PDF