Clinical Pharmacokinetic Profile of Modafinil

@article{Robertson2003ClinicalPP,
  title={Clinical Pharmacokinetic Profile of Modafinil},
  author={P. Robertson and E. Hellriegel},
  journal={Clinical Pharmacokinetics},
  year={2003},
  volume={42},
  pages={123-137}
}
Modafinil is a unique wake-promoting agent for oral administration. Its pharmacological properties are distinct from those of other CNS agents, and it selectively targets neuronal pathways in the sleep/wake centres of the brain.After single or multiple oral doses, modafinil is readily absorbed, reaching maximum plasma concentrations at 2–4 hours after administration and pharmacokinetic steady state within 2–4 days. Its pharmacokinetics are dose-independent between 200 and 600 mg/day. The… Expand
198 Citations
Population Pharmacokinetics of Modafinil and Its Acid and Sulfone Metabolites in Chinese Males
  • 4
  • Highly Influenced
Pharmacokinetic and pharmacodynamic of the cognitive enhancer modafinil: Relevant clinical and forensic aspects
  • 2
  • Highly Influenced
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 34 REFERENCES
Hepatic Drug Metabolism and Aging
  • 193
...
1
2
3
4
...