Clinical Isolates of Shiga Toxin 1a–Producing Shigella flexneri with an Epidemiological Link to Recent Travel to Hispañiola

@inproceedings{Gray2014ClinicalIO,
  title={Clinical Isolates of Shiga Toxin 1a–Producing Shigella flexneri with an Epidemiological Link to Recent Travel to Hispa{\~n}iola},
  author={Miranda D. Gray and Keith A. Lampel and Nancy A. Strockbine and Reinaldo E. Fern{\'a}ndez and Angela R. Melton-Celsa and Anthony T Maurelli},
  booktitle={Emerging infectious diseases},
  year={2014}
}
Shiga toxins (Stx) are cytotoxins involved in severe human intestinal disease. These toxins are commonly found in Shigella dysenteriae serotype 1 and Shiga-toxin-producing Escherichia coli; however, the toxin genes have been found in other Shigella species. We identified 26 Shigella flexneri serotype 2 strains isolated by public health laboratories in the United States during 2001-2013, which encode the Shiga toxin 1a gene (stx1a). These strains produced and released Stx1a as measured by… CONTINUE READING
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