Clinical Investigation : Head and Neck Cancer A Single-Institutional Experience of 15 Years of Treating T 3 Laryngeal Cancer With Primary Radiotherapy , With or Without Chemotherapy

@inproceedings{AlMamgani2012ClinicalI,
  title={Clinical Investigation : Head and Neck Cancer A Single-Institutional Experience of 15 Years of Treating T 3 Laryngeal Cancer With Primary Radiotherapy , With or Without Chemotherapy},
  author={Abrahim Al-Mamgani and Lisa Tans and Peter H. van Rooij and Peter C. Levendag},
  year={2012}
}
Patients with T3 laryngeal cancer achieved a good LC with RT alone. However, the addition of chemotherapy to the RT significantly improved LC, laryngectomyfree survival, and DM-free survival. Cancer-specific survival was also improved with chemoradiation, albeit statistically not significant. The improvement achieved by chemoradiation was not associated with increase in late toxicity or deterioration of QoL or voice-handicapindex scores. Salvage laryngectomy is successful in patients who do not… CONTINUE READING

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