Clinical Efficiency of Topical Calcipotriol/Betamethasone Treatment in Psoriasis Relies on Suppression of the Inflammatory TNFα - IL-23 - IL-17 Axis.

Abstract

The effects of topical calcipotriol/betamethasone combination therapy and betamethasone monotherapy on inflammatory T-cell numbers and molecular markers were compared in patients with psoriasis. Combination therapy down-regulated the expression of tumour necrosis factor (TNF)-α, interleukin (IL)-23A, IL-17A, S100A7, CCL-20 and interferon (IFN)-γ in skin and… (More)
DOI: 10.2340/00015555-2579

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@article{Kubin2017ClinicalEO, title={Clinical Efficiency of Topical Calcipotriol/Betamethasone Treatment in Psoriasis Relies on Suppression of the Inflammatory TNFα - IL-23 - IL-17 Axis.}, author={Minna E Kubin and Nina Kokkonen and Riitta Palatsi and P{\"a}ivi M. H{\"a}gg and Juha P. V{\"a}yrynen and Virpi Glumoff and K. M. Haapasaari and Tiina L Hurskainen and Kaisa Tasanen}, journal={Acta dermato-venereologica}, year={2017}, volume={97 4}, pages={449-455} }