Clinical Course of acute-on-chronic liver failure syndrome and effects on prognosis.

  title={Clinical Course of acute-on-chronic liver failure syndrome and effects on prognosis.},
  author={Thierry Gustot and J. Fern{\'a}ndez and Elisabet Kadar Garcia and Filippo Morando and Paolo Caraceni and Carlo Alessandria and Wim Laleman and Jonel Trebicka and L Elkrief and Corinna Hopf and Pablo A Sol{\'i}s-Mu{\~n}oz and Faouzi Saliba and Stefan Zeuzem and Augustin Albillos and Daniel Benten and Jos{\'e} Luis Montero-{\'A}lvarez and Maria Teresa Chivas and Mar Concepci{\'o}n and J. M. Mass{\'o} C{\'o}rdoba and Aiden P McCormick and Rudolf E. Stauber and Wolfgang Vogel and Andrea de Gottardi and Tania Mara Welzel and Marco Domenicali and Alessandro Risso and Julia A. Wendon and Carme Deulofeu and Paolo Angeli and François Durand and Marco Pavesi and Alexander L Gerbes and Rajiv Jalan and Richard Moreau and Pere Gin{\`e}s and Mauro Bernardi and Vicente Arroyo},
  volume={62 1},
UNLABELLED Acute-on-chronic liver failure (ACLF) is characterized by acute decompensation (AD) of cirrhosis, organ failure(s), and high 28-day mortality. We investigated whether assessments of patients at specific time points predicted their need for liver transplantation (LT) or the potential futility of their care. We assessed clinical courses of 388 patients who had ACLF at enrollment, from February through September 2011, or during early (28-day) follow-up of the prospective multicenter… CONTINUE READING
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