Clinical Challenges Associated with Universal Screening for Lynch Syndrome-Associated Endometrial Cancer.

Abstract

Universal testing for Lynch syndrome is now a routine component of the diagnostic work-up of endometrial cancer patients. The purpose of this study was to identify prospectively the barriers to universal screening based on a tissue testing approach [microsatellite instability (MSI) analysis, IHC for DNA mismatch repair proteins, and MLH1 methylation… (More)
DOI: 10.1158/1940-6207.CAPR-16-0219

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