Clinical Application of Multigene Panels: Challenges of Next-Generation Counseling and Cancer Risk Management

@inproceedings{Slavin2015ClinicalAO,
  title={Clinical Application of Multigene Panels: Challenges of Next-Generation Counseling and Cancer Risk Management},
  author={Thomas Paul Slavin and Mariana Niell-Swiller and Ilana Solomon and Bita Nehoray and Christina Rybak and Kathleen R. Blazer and Jeffrey N. Weitzel},
  booktitle={Front. Oncol.},
  year={2015}
}
  • Thomas Paul Slavin, Mariana Niell-Swiller, +4 authors Jeffrey N. Weitzel
  • Published in Front. Oncol. 2015
  • Medicine
  • BACKGROUND Multigene panels can be a cost- and time-effective alternative to sequentially testing multiple genes, especially with a mixed family cancer phenotype. However, moving beyond our single-gene testing paradigm has unveiled many new challenges to the clinician. The purpose of this article is to familiarize the reader with some of the challenges, as well as potential opportunities, of expanded hereditary cancer panel testing. METHODS We include results from 348 commercial multigene… CONTINUE READING

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