Clinical Analysis of Adverse Drug Reactions between Vincristine and Triazoles in Children with Acute Lymphoblastic Leukemia

@inproceedings{Yang2015ClinicalAO,
  title={Clinical Analysis of Adverse Drug Reactions between Vincristine and Triazoles in Children with Acute Lymphoblastic Leukemia},
  author={Lihua Yang and Lihua Yu and Xinxin Chen and Yanqun Hu and Bin Wang},
  booktitle={Medical science monitor : international medical journal of experimental and clinical research},
  year={2015}
}
BACKGROUND Vincristine (VCR) is a major chemotherapy drug for treatment of childhood acute lymphoblastic leukemia (ALL). Triazole antifungal drugs (AFD) are the main agents for the prevention/treatment of invasive fungal infection (IFI), a common complication during the treatment of ALL. This study investigated the adverse drug reactions (ADRs) between VCR and AFD. MATERIAL AND METHODS A retrospective study was performed on 68 children with ALL (39 boys and 29 girls, median age: 5 years) who… CONTINUE READING
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