Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: A study of 133 patients diagnosed with new standard criteria

@article{Montplaisir1997ClinicalPA,
  title={Clinical, polysomnographic, and genetic characteristics of restless legs syndrome: A study of 133 patients diagnosed with new standard criteria},
  author={Jacques Montplaisir and Sylvie Boucher and Gaétan Poirier and Gilles Lavigne and Odile Lapierre and Paul Lesp{\'e}rance},
  journal={Movement Disorders},
  year={1997},
  volume={12}
}
One hundred thirty‐three cases of restless legs syndrome (RLS), diagnosed with criteria recently formulated by an international study group, were studied by questionnaire and with all‐night polysomnographic recordings. Results show that RLS starts at a mean age of 27.2 years and before age 20 in 38.3% of patients. Symptoms often appear in one leg only and also involve upper limbs in about half of all cases. Most patients (94%) report sleep‐onset insomnia or numerous nocturnal awakenings due to… 
Clinical and polysomnographic features of patients with Restless Legs Syndrome.
TLDR
Clinical and polysomnographic features in patients treated for restless leg syndrome are revealed and the compatibility of sleep data and clinical features are examined to examine.
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TLDR
It is suggested that there is considerable delay before appropriate therapy in RLS, with a large number of patients having EDS and insomnia among others, is the commonest presenting feature.
Polysomnography findings in patients with restless legs syndrome and in healthy controls: a comparative observational study.
TLDR
The largest polysomnography study to date that compares patients with idiopathic RLS with age- and sex-matched healthy subjects demonstrates markedly fragmented sleep with deterioration of both NREM and REM sleep in RLS patients.
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TLDR
RLS is a clinically pleomorphic syndrome, reflecting the contribution of multiple genetic and acquired factors in the pathogenesis of RLS.
Restless legs syndrome.
TLDR
A large number of studies have now confirmed that dopamine agonists can also be effective in RLS therapy, and that this treatment seems to involve less risk for augmentation.
Prevalence of restless legs syndrome among men aged 18 to 64 years: An association with somatic disease and neuropsychiatric symptoms
TLDR
Results show that restless legs syndrome is common among men and it is hypothesized that RLS may be associated with several somatic and neuropsychiatric symptoms.
Prevalence and Characteristics of Periodic Limb Movements during Sleep in Korean Adult Patients with Restless Legs Syndrome.
  • Jung-Won Shin, Y. Koo, Ki-Young Jung
  • Medicine, Psychology
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
  • 2016
TLDR
The prevalence and characteristics of periodic limb movements during sleep (PLMS) in Korean patients with restless legs syndrome was lower than that observed in Western countries, but the characteristics of PLMS were not different.
Gender differences in clinical, laboratory and polysomnographic features of restless legs syndrome
TLDR
Restless legs syndrome severity as measured by validated scales was worse in women, while periodic leg movements during sleep indices were higher in men, suggesting a possible gender difference in phenotypical presentation of restless legs syndrome.
Childhood‐onset restless legs syndrome
TLDR
It is concluded that iron deficiency and a strong family history are characteristic of childhood‐onset restless legs syndrome.
Excessive Daytime Sleepiness in Idiopathic Restless Legs Syndrome: Characteristics and Evolution under Dopaminergic Treatment
TLDR
In a series of RLS patients, EDS was common, characterized by longer sleep (PSG) and reduced sleep latencies on MSLT, and under dopaminergic treatment, both RLS severity and ESS improved.
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