Clinical, pathological, immunohistochemical and molecular characterization of feline chronic gingivostomatitis

@article{Rolim2017ClinicalPI,
  title={Clinical, pathological, immunohistochemical and molecular characterization of feline chronic gingivostomatitis},
  author={Ver{\^o}nica Machado Rolim and Saulo Petinatti Pavarini and Fabr{\'i}cio Souza Campos and V{\'i}viam Nunes Pignone and Cl{\'a}udia Faraco and Marcelo de Souza Muccillo and Paulo Michel Roehe and Fernanda Vieira Amorim Da Costa and David Driemeier},
  journal={Journal of Feline Medicine and Surgery},
  year={2017},
  volume={19},
  pages={403 - 409}
}
Objectives This study presents the clinical, pathological, immunohistochemical and molecular characterization of 26 cats with feline chronic gingivostomatitis (FCG. [...] Key Method Results The main clinical findings were dysphagia (88.2%), halitosis (76.5%), sialorrhea (47.1%), weight loss (41.2%), intense oral discomfort (35.3%), oral hemorrhage (17.6%), and lackluster and fragile coat (11.8%). Gross inspection revealed bilateral lesions across the palatoglossal fold to the lateral tongue base. The lesions…Expand
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References

SHOWING 1-10 OF 31 REFERENCES
Immunohistochemical characterization of oral mucosal lesions in cats with chronic gingivostomatitis.
TLDR
Findings indicate that the glossopalatine mucosal lesions in FCGS represent a complex, chronic and destructive inflammatory process affecting the epithelium and lamina propria, with frequent extension into submucosal tissues. Expand
Prevalence of feline chronic gingivo-stomatitis in first opinion veterinary practice
TLDR
The prevalence of FCGS in a convenience based sample of cats visiting first opinion small animal veterinary practices was 0.7%, and no statistically significant difference was found when the age, sex and breed of cats with FCGS were compared to data from cats without the condition. Expand
Immunohistological evaluation of feline herpesvirus-1 infection in feline eosinophilic dermatoses or stomatitis
TLDR
FHV-1 should be considered in cats with severe ulcerative cutaneous or oral lesions, unresponsive to corticosteroid treatment, with or without concurrent or historical signs of upper respiratory tract or ocular disease more typical of FHv-1. Expand
Novel bacterial phylotypes associated with the healthy feline oral cavity and feline chronic gingivostomatitis.
TLDR
The presence of a group of novel, previously unidentified bacteria that are associated with the feline oral cavity in both health and disease suggests the presence of the first putative novel species in the oral cavity of cats with and without FCGS. Expand
Ulcerative facial and nasal dermatitis and stomatitis in cats associated with feline herpesvirus 1.
TLDR
Polymerase chain reaction (PCR) specific for feline herpesvirus 1 on DNA extracted from fresh-frozen or formalin-fixed paraffin-embedded biopsy samples and/or consensus primer PCR with DNA sequencing performed on DNA extraction samples from seven cats revealed that the virus was indistinguishable from f cat herpesv virus 1. Expand
Evaluation of the association of Bartonella species, feline herpesvirus 1, feline calicivirus, feline leukemia virus and feline immunodeficiency virus with chronic feline gingivostomatitis
TLDR
Assay results failed to correlate to the presence of GS in the group of cats studied, and all cats were negative for FeLV. Expand
Isolation and identification of feline calicivirus and feline herpesvirus in Southern Brazil
TLDR
The results suggest that a carrier state is common for both viruses in the evaluated population of cats in Rio Grande do Sul State, Brazil and further studies relating to the molecular characterization of viruses and vaccine efficacy are necessary. Expand
Cessation of feline calicivirus shedding coincident with resolution of chronic gingivostomatitis in a cat.
TLDR
Resolution of clinical signs of FGS coincided with the cessation of FCV shedding, and this is the first report documenting such an association. Expand
Feline Herpesvirus-1
  • D. Gould
  • Medicine
  • Journal of feline medicine and surgery
  • 2011
TLDR
Treating FHV-1 ocular disease with a wide range of antiviral treatments requires good clinical judgement, with assessment of factors such as severity and stage of clinical disease, patient and owner compliance, and financial considerations. Expand
Chronic oral infections of cats and their relationship to persistent oral carriage of feline calici-, immunodeficiency, or leukemia viruses.
TLDR
FIV-infected cats that were coinfected with either FCV, or with FCV and FeLV, had the highest prevalence of oral cavity infections and the most severe oral lesions. Expand
...
1
2
3
4
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