Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia.

@article{Olopade1992ClinicalMA,
  title={Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia.},
  author={Olofunmilayo I. Olopade and Maya Thangavelu and Richard A Larson and Rosemarie Mick and Areta Kowal-Vern and Harold R. Schumacher and Michelle M Le Beau and James W. Vardiman and J D Rowley},
  journal={Blood},
  year={1992},
  volume={80 11},
  pages={2873-82}
}
We have performed a retrospective analysis of the clinical, morphologic, and cytogenetic findings in 26 patients diagnosed between January 1969 and September 1991 with acute erythroblastic leukemia de novo (EL or AML-M6). Clonal chromosomal abnormalities were found in 20 (77%) patients (95% confidence interval [CI], 61% to 93%). Loss of all or part of the long arm (q) of chromosomes 5 and/or 7 was observed in 17 (65%) patients (95% CI, 47% to 83%). In addition, the karyotypes were often complex… CONTINUE READING

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