Clinical, microbial, and biochemical aspects of the exfoliative toxins causing staphylococcal scalded-skin syndrome.

@article{Ladhani1999ClinicalMA,
  title={Clinical, microbial, and biochemical aspects of the exfoliative toxins causing staphylococcal scalded-skin syndrome.},
  author={Shamez Ladhani and Christopher L. Joannou and D P Lochrie and Robert Evans and S M Poston},
  journal={Clinical microbiology reviews},
  year={1999},
  volume={12 2},
  pages={224-42}
}
The exfoliative (epidermolytic) toxins of Staphylococcus aureus are the causative agents of the staphylococcal scalded-skin syndrome (SSSS), a blistering skin disorder that predominantly affects children. Clinical features of SSSS vary along a spectrum, ranging from a few localized blisters to generalized exfoliation covering almost the entire body. The toxins act specifically at the zona granulosa of the epidermis to produce the characteristic exfoliation, although the mechanism by which this… CONTINUE READING
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