Clinical, immunological, and immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sjögren's syndrome (pSS): a European multicentre study.

@article{Tzioufas2002ClinicalIA,
  title={Clinical, immunological, and immunogenetic aspects of autoantibody production against Ro/SSA, La/SSB and their linear epitopes in primary Sj{\"o}gren's syndrome (pSS): a European multicentre study.},
  author={Athanasios G. Tzioufas and Ralf Wassmuth and Urania Dafni and Apostolia Guialis and H-J Haga and David Alan Isenberg and Roland Jonsson and Joachim. R. Kalden and Hans P. Kiener and Constantinos E Sakarellos and Nurhan Sutcliffe and Claudio Vitali and Erin Yiannaki and H M Moutsopoulos},
  journal={Annals of the rheumatic diseases},
  year={2002},
  volume={61 5},
  pages={
          398-404
        }
}
OBJECTIVES To investigate the clinical and immunogenetic aspects of antibody formation against Ro/SSA and La/SSB as well as their linear B cell epitopes in patients with primary Sjögren's syndrome (pSS) from different European countries. PATIENTS AND METHODS Ninety patients with pSS from six European centres were studied. Serum samples from all patients were tested in a control laboratory for anti-Ro/SSA and anti-La/SSB autoantibodies by RNA precipitation assay and autoantibodies to the… CONTINUE READING
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