Clinical, agricultural, and evolutionary biology of myostatin: a comparative review.

@article{Rodgers2008ClinicalAA,
  title={Clinical, agricultural, and evolutionary biology of myostatin: a comparative review.},
  author={Buel D. Rodgers and Dilip K Garikipati},
  journal={Endocrine reviews},
  year={2008},
  volume={29 5},
  pages={513-34}
}
The discovery of myostatin and our introduction to the "Mighty Mouse" over a decade ago spurred both basic and applied research and impacted popular culture as well. The myostatin-null genotype produces "double muscling" in mice and livestock and was recently described in a child. The field's rapid growth is by no means surprising considering the potential benefits of enhancing muscle growth in clinical and agricultural settings. Indeed, several recent studies suggest that blocking myostatin's… CONTINUE READING
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