CliniCal and moleCular neuroimaging CharaCteristiCs of Brazilian patients with parkinson ’ s disease and mutations in PARK 2 or PARK 8 genes

@inproceedings{Barsottini2009CliniCalAM,
  title={CliniCal and moleCular neuroimaging CharaCteristiCs of Brazilian patients with parkinson ’ s disease and mutations in PARK 2 or PARK 8 genes},
  author={O G P Barsottini and Andre C. Fel{\'i}cio and Patr{\'i}cia Aguiar and Cl{\'e}cio de Oliveira Godeiro-J{\'u}nior and Ming Chi Shih and Marcelo Queiroz Hoexter and Rodrigo Affonseca Bressan and Henrique Ballalai Ferraz and Luiz Augusto F. Andrade},
  year={2009}
}
  • O G P Barsottini, Andre C. Felício, +6 authors Luiz Augusto F. Andrade
  • Published 2009
Objective: To describe clinical and neuroimaging (SPECT) characteristics of Brazilian patients with Parkinson’s disease (PD) and mutations in PARK2 or PARK8 genes. Method: A total of 119 patients meeting clinical criteria for PD were evaluated. Results: Of all patients studied, 13 had mutations in either PARK2 (n=9) or PARK8 genes (n=4). No statistically significant differences in clinical characteristics in both groups were seen. SPECT with [Tc] TRODAT-1 showed significant differences between… CONTINUE READING