Clickable Poly(ionic liquids): A Materials Platform for Transfection.
@article{Freyer2016ClickablePL, title={Clickable Poly(ionic liquids): A Materials Platform for Transfection.}, author={Jessica L. Freyer and Spencer D. Brucks and Graham Gobieski and S. T. Russell and Carrie E. Yozwiak and Mengzhen Sun and Zhixing Chen and Yivan Jiang and Jeffrey S Bandar and B. Stockwell and T. Lambert and L. Campos}, journal={Angewandte Chemie}, year={2016}, volume={55 40}, pages={ 12382-6 } }
The potential applications of cationic poly(ionic liquids) range from medicine to energy storage, and the development of efficient synthetic strategies to target innovative cationic building blocks is an important goal. A post-polymerization click reaction is reported that provides facile access to trisaminocyclopropenium (TAC) ion-functionalized macromolecules of various architectures, which are the first class of polyelectrolytes that bear a formal charge on carbon. Quantitative conversions… CONTINUE READING
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References
SHOWING 1-10 OF 55 REFERENCES
Facile and general preparation of multifunctional main-chain cationic polymers through application of robust, efficient, and orthogonal click chemistries.
- Chemistry, Medicine
- Journal of the American Chemical Society
- 2012
- 67
The evolution of cyclopropenium ions into functional polyelectrolytes
- Materials Science, Medicine
- Nature communications
- 2015
- 31
- PDF
Amphipathic homopolymers for siRNA delivery: probing impact of bifunctional polymer composition on transfection.
- Chemistry, Medicine
- Biomacromolecules
- 2014
- 33
Biodegradable poly(amine-co-ester) terpolymers for targeted gene delivery.
- Materials Science, Medicine
- Nature materials
- 2011
- 273
Polymeric supramolecular assemblies based on multivalent ionic interactions for biomedical applications
- Materials Science
- 2014
- 39
Nanostructured functional materials prepared by atom transfer radical polymerization.
- Chemistry, Medicine
- Nature chemistry
- 2009
- 938
Tunable, high modulus hydrogels driven by ionic coacervation.
- Materials Science, Medicine
- Advanced materials
- 2011
- 228
Effect of Nanoscale Morphology on the Conductivity of Polymerized Ionic Liquid Block Copolymers
- Materials Science
- 2011
- 191
- PDF